EuMMCR intends to offer a Chimera Production Service to generate mice from the EUCOMM ES cell resource upon request.
In the EUCOMM program more than 250 chimeras and germ line transmissions have been established. They have been entered into the database of EUMODIC and are available via EMMA. The overall success rate of germ line transmission of any given clone is currently about 60% based on experience of four participating centers.
The production of IKMC mouse lines in the recent years has been done by the International Mouse Phenotyping Consortium (IMPC). If you would like to work with a specific mouse line and you don’t have the capacity to perform your own blastocyst injections etc., please contact IMPC and request that your desired mouse line is introduced into the IMPC pipeline.